CD51/CD61 Antikörper

Produktnummer ABIN2567844

Der Maus Monoklonal Anti-CD51/CD61 Antikörper wurde für FACS und Func validiert. Er ist geeignet, CD51/CD61 in Proben von Human zu detektieren.

Kurzübersicht für CD51/CD61 Antikörper (ABIN2567844)

Target: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD51/CD61 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: 23C6

Produktdetails anti-CD51/CD61 Antikörper

Spezifität: The 23C6 monoclonal antibody specifically reacts with the human CD51/61 Molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor.

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C. Do not freeze.

Details zu CD51/CD61

Target: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Andere Bezeichnung: CD51/CD61

Hintergrund: The 23C6 monoclonal antibody specifically reacts with the human CD51/61 Molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor. The complex binds to other ligands such as CD29, fibrinogen, fibrinectin, vWf, laminin, and thrombospondin. It is expressed by endothelial cells, osteoclasts, melanoma cells, and at low levels on platelets and macrophages. The 23C6 antibody is reported to be able to block the receptors ability to form interactions with some of its ligands.

Gen-ID: 3685, 3690

UniProt: P06756, P05106